All Posts: research
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Case Study Reveals Important New Details About Rare Second Cancers Related to CAR-T Therapy
A new, detailed analysis of a patient’s second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.
Category: News Release
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Experimental Therapy Shows Promise in Pancreatic Cancer Clinical Trial
Clinicians at Georgetown University’s Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda). Immunotherapy drugs alone have not shown to be responsive to pancreatic cancer.
Category: News Release
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Cognitive Declines Preceding Alzheimer’s Diagnosis Lead to Credit Card, Mortgage Delinquency
In the years prior to an Alzheimer’s disease or other memory disorder diagnosis, credit scores begin to weaken and payment delinquency begins to increase, concludes new research led by Georgetown University. The findings show consistent deterioration in these financial outcomes over the quarters leading up to diagnosis and that credit card and mortgage delinquencies, specifically, both increase substantially prior to diagnosis.
Category: News Release
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Structural Inequities Amplify Homelessness Challenges for Pregnant People in Washington, DC
New research conducted with Washington, DC, residents who experienced homelessness during pregnancy sheds light on the intersection of homelessness, pregnancy and racial inequities. The findings underscore the urgent need for policy and practice changes to support vulnerable populations.
Category: News Release
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New Study: Analysis Supports New Recommendation to Begin Mammogram Screening at 40
Georgetown Lombardi’s Jeanne Mandelblatt, MD, MPH, and Amy Trentham-Dietz, PhD, of University of Wisconsin Carbone Cancer Center, were lead authors of a study informing the updated final recommendation of the United States Preventive Services Task Force regarding breast cancer screening, released April 30
Category: News Release
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The Aspirin Conundrum: Navigating Negative Results, Age, Aging Dynamics and Equity
A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers from Georgetown University’s Lombardi Comprehensive Cancer Center. They outline their concerns in an editorial accompanying the study’s findings published April 29 in the JAMA.
Category: News Release
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Perinatal Transmission of HIV Can Lead to Cognitive Deficits
Perinatal transmission of HIV to newborns is associated with serious cognitive deficits as children grow older, according to a detailed analysis of 35 studies conducted by Georgetown University Medical Center neuroscientists. The finding helps pinpoint the geographic regions and factors that may be important for brain development outcomes related to perinatal HIV infection: mother-to-child HIV transmission during pregnancy, labor and delivery, or breastfeeding.
Category: News Release
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A Third of Women Experience Migraines Associated with Menstruation, Most Commonly When Premenopausal
A third of the nearly 20 million women who participated in a national health survey reported migraines during menstruation, and of them, 11.8 million, or 52.5%, were premenopausal. The analysis was conducted by researchers at Georgetown University Medical Center and Pfizer, Inc., which makes a migraine medication.
Category: News Release
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Abnormal Brain Structure Identified in Children with Developmental Language Problems
A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical Center neuroscientists.
Category: News Release
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Inflammation and Diabetic Kidney Disease: Why Mitochondria Matter
Komuraiah Myakala, PhD, a research instructor at Georgetown University, is conducting research on Type 2 diabetic disease progression that helps demonstrate the importance of mitochondrial function in renal disease, particularly in diabetes.
Category: GUMC Stories