All Posts: brain
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Nilotinib Appears Safe and Affects Biomarkers in Alzheimer’s Disease Clinical Trial
WASHINGTON (May 29, 2020) — A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy. The results […]
Category: News Release
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Georgetown’s José Merino Becomes Editor-In-Chief of the World’s Leading Clinical Neurology Journal
(April 18, 2020) — José G. Merino, MD, MPhil, FAHA, FAAN, professor of neurology at Georgetown University School of Medicine, became interested in medical journals as a medical student; he later gained experience in peer-reviewing journals as a fellow. Now, he will merge his longtime interest and extensive experience as he begins a 10-year term […]
Category: GUMC Stories
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Zooming in on Brain Circuits Allows Researchers to Stop Seizure Activity
WASHINGTON (December 16, 2019) — A team of neuroscientists at Georgetown University Medical Center have found, in animal models, that they can “switch off” epileptic seizures. The findings, published online in Proceedings of the National Academy of Sciences (PNAS), provide the first evidence that while different types of seizures start in varied areas of the […]
Category: News Release
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Nilotinib Appears Safe in Parkinson’s Trial; Drug Thought to Allow Dopamine Replenishment
WASHINGTON (December 16, 2019) — A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson’s disease finds that it is reasonably safe and well tolerated. Researchers also report finding an increase in dopamine, the chemical lost as a result of neuronal destruction, and a decrease in neurotoxic proteins in the brain among […]
Category: News Release
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Veterans Study Suggests Two Subtypes of Gulf War Illness
WASHINGTON (December 12, 2019) — Brain imaging of veterans with Gulf War illness show varying abnormalities after moderate exercise that can be categorized into two distinct groups — an outcome that suggests a more complex illness that previously thought. Researchers at Georgetown University Medical Center, using functional magnetic resonance imaging (fMRI), have shown the Gulf […]
Category: News Release
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Brain Studies Show Chronic Fatigue Syndrome and Gulf War Illness are Distinct Conditions
CHICAGO (October 23, 2019) — Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise). Now, neuroscientists at Georgetown University Medical Center have evidence, derived from human brain studies, that GWI and […]
Category: News Release
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Exposure to Environmental PCBs Impairs Brain Function in Mice
CHICAGO (October 22, 2019) — Human-made toxic chemicals that linger indefinitely in the environment disrupt the performance of critical helper cells in the mouse brain, leading to impaired function over long-term exposures, say neuroscientists at Georgetown University Medical Center. Their study, believed to be the first to test polychlorinated biphenyls (PCBs) in astrocytes — cells […]
Category: News Release
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Maguire-Zeiss Named New Chair of Department of Neuroscience
(August 29, 2019) — Since joining Georgetown’s faculty in 2007, Kathy Maguire-Zeiss, PhD, has taken on many roles. In addition to being a professor of neuroscience, she directs the Interdisciplinary Program in Neuroscience (IPN), the Center for Neural Injury and Recovery, the master’s degree program in integrative neuroscience and the T32 Training Program in Neural […]
Category: GUMC Stories
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Shedding Light on Lewy Body Disease
(May 30, 2019) — Though many people are familiar with Parkinson’s and Alzheimer’s diseases, fewer have heard of Lewy body dementia, a neurodegenerative disorder with similar symptoms. “I think more awareness needs to be out there because Lewy body disease is probably just as prevalent as Parkinson’s,” said Fernando Pagan, MD (M’96), professor of neurology […]
Category: GUMC Stories
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Georgetown University Launches Clinical Trial for Lewy Body Dementia
MEDIA CONTACT:(for members of the press only) Karen Teberkm463@georgetown.edu PATIENT INFORMATION:Joy Arellanomja6@gunet.georgetown.edu WASHINGTON (May 30, 2019) — Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved […]
Category: News Release