All Posts:Alzheimer's disease
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Georgetown Study Explores THC/CBD Combination to Reduce Dementia-related Agitation at the End of Life
In a first-of-its-kind clinical trial, the Georgetown University Medical Center Memory Disorders Program will study the effects of an oral drug called T2:C100, which is comprised of two components found in marijuana — THC and CBD. The goal of the study is to investigate its potential to decrease agitation experienced by those with dementia at the end of life.
Category: News Release
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Looking for a Breakthrough in Alzheimer’s Disease
After nearly two decades of clinical trials failing to deliver new treatments, Alzheimer’s disease researchers and clinicians, as well as patients and their families, have expressed cautious optimism regarding the new medications — and their implications for the future.
Category: GUMC Stories
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Key Mental Abilities Can Actually Improve During Aging
WASHINGTON (August 19, 2021) — It’s long been believed that advancing age leads to broad declines in our mental abilities. Now, new research from Georgetown University Medical Center offers surprisingly good news by countering this view. The findings, published August 19, 2021, in Nature Human Behavior, show that two key brain functions, which allow us […]
Category: News Release
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Immune-Compromised People with HIV, APOE4 Gene May Have a Compounded Risk for Alzheimer’s
WASHINGTON (February 22, 2021) — People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer’s disease-related gene variant APOE4 might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after […]
Category: News Release
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Early-life Education Improves Memory in Old Age — Especially for Women
WASHINGTON (June 5, 2020) — Education appears to protect older adults, especially women, against memory loss, according to a study by investigators at Georgetown University Medical Center, published in the journal Aging, Neuropsychology, and Cognition. The results suggest that children — especially girls — who attend school for longer will have better memory abilities in […]
Category: News Release
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Nilotinib Appears Safe and Affects Biomarkers in Alzheimer’s Disease Clinical Trial
WASHINGTON (May 29, 2020) — A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy. The results […]
Category: News Release
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Donors Get Firsthand Look at How Funds for New Medical Research Are Used
(February 10, 2020) — Current and potential donors to the Partners in Research program were given a rare look into the laboratories where medical tests and drug trials get their start. During the recent “Night at the Lab” tour on the Georgetown University Medical Center campus, participants walked down white halls lined with posters of […]
Category: GUMC Stories
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Heightened Risk of Adverse Financial Changes Before Alzheimer’s Diagnosis
WASHINGTON (October 25, 2019) — Prior to an Alzheimer’s diagnosis, a person in the early stages of the disease faces a heightened risk of adverse financial outcomes — a likely consequence of compromised decision-making when managing money, in addition to exploitation and fraud by others. That is the disquieting conclusion of a study published in […]
Category: News Release
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Novel Agent Flips on ‘Garbage Disposal’ in Neurons, Eliminating Toxic Brain Proteins in Mice
CHICAGO (October 22, 2019) — Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson’s and Alzheimer’s diseases, and improves cognitive and motor behavior. The team presented their findings about the agent, CM101 (also known as BK40143), in […]
Category: News Release
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Shedding Light on Lewy Body Disease
(May 30, 2019) — Though many people are familiar with Parkinson’s and Alzheimer’s diseases, fewer have heard of Lewy body dementia, a neurodegenerative disorder with similar symptoms. “I think more awareness needs to be out there because Lewy body disease is probably just as prevalent as Parkinson’s,” said Fernando Pagan, MD (M’96), professor of neurology […]
Category: GUMC Stories