Gene Variations, Alcohol, and an Association with Breast Cancer Risk
May 2, 2008
Specific variations within two genes involved with alcohol metabolism are associated with an increased risk for breast cancer in postmenopausal women, according to a new study presented at the annual meeting of the American Assocation for Cancer Research.
The work, conducted by research groups led by Peter Shields, M.D., professor of medicine and oncology at Lombardi Comprehensive Cancer Center and Jo Freudenheim, Ph.D., chair of social and preventive medicine at the State University of New York at Buffalo, indicates that sequence variations within the genes ADH1B and ADH1C may as much as double a postmenopausal woman drinker’s risk for breast cancer.
“We found that variations in two genes coding for the alcohol dehydrogenase enzyme increase the risk of breast cancer among women who drink,” says lead author Catalin Marian, M.D., Ph.D., a research instructor of cancer genetics and epidemiology at Lombardi. “The higher their alcohol consumption, the higher their risk.”
For more information, click here.
Submit your news at any time to the GUMC Office of Communications at gumccomm@georgetown.edu.
More Research News
Browse recent items in this category.
-
Georgetown University and Georgetown University Medical Center Researchers Presented More than 100 Scientific Abstracts at Neuroscience 2008
Researchers from Georgetown University and Georgetown University Medical Center’s departments of neuroscience, psychology, physiology and biophysics presented more than 100 research abstracts at the Society for Neuroscience’s 38th annual meeting
12/4/2008 -
Georgetown University Medical Center Hosts Inaugural Baldev R. Bhussry Lecture
Dr. Gerald M. Crabtree of the School of Medicine at Stanford University presented his lecture, “Understanding the Words of Chromatin Remodeling
12/3/2008 -
Georgetown’s Lombardi Comprehensive Cancer Center Launches ShopforCancerCures.org to Raise Money for Cancer Research
Lombardi Cancer Center and Mall Networks, the leading provider of merchant-funded loyalty shopping solutions, today announced the launch of a new online shopping mall to raise money for cancer research.
11/18/2008 -
Non-White Medical Students Reject Therapies Typically Associated with Their Culture While White Students Embrace CAM
Survey of medical students measures attitude of complementary and alternative medicine during four years of medical training.
11/18/2008 -
“New” Estrogen Receptor Found to be Key Player in Tamoxifen Resistance
Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world’s largest-selling breast cancer prevention and treatment drug.
11/18/2008 -
Doo Wop Concert Raises Money for Lombardi Cancer Programs
Marvin McIntyre and Family host D.C.'s first Doo Wop concert to benefit programs at Lombardi
9/29/2008 -
Lombardi's Cancer Survivorship Program Receives Donation from Hyundai Hope on Wheels Tour
Dr. Aziza Shad and her pediatric patients at Lombardi received a generous helping hand last week at the Hyundai Hope on Wheels Handprint Ceremony when Don Reilly, co-owner of Alexandria Hyundai, presented LCCC with a donation of $40,000.
9/29/2008 -
Subha Madhavan Joins Faculty at Lombardi Comprehensive Cancer Center
Subha Madhavan joined the Lombardi Comprehensive Cancer Center on September 15 as the first Director of Clinical Research Informatics and Research Assistant Professor of Oncology.
9/23/2008
More Education News
Browse recent items in this category.
-
Match Day Marks Emotional Rite of Passage for Medical Students
Georgetown medical students participated in the annual ritual that takes place around the country on the third Thursday in March—Match Day, the process that helps decide where they will spend their four years of residency.
4/1/2009 -
NHS Honors December Grads
NHS honored 95 students who completed their bachelor’s and master’s degrees in nursing in the fall 2008 semester at a completion ceremony on Dec. 13.
12/19/2008 -
School of Medicine Program Featured in "Academic Physician and Scientist"
Check out the latest issue of Academic Physician and Scientist to read the article about the Mind-Body Skills Program at Georgetown University Medical Center's School of Medicine.
12/10/2008